Dr. Tobias R. Kießling

Scientific Software Solutions

Custom Algorithms · Biological Image Analysis · High-Performance Data Pipelines

Complex data requires precision tools. I engineer custom software solutions for biotechnology, medical technology, and research. From the initial idea to a production-ready data pipeline – delivering reliability for over 10 years.

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Years Freelancing

Publications

Industry Partners

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Client Rating

What I Do

Core Expertise

Where off-the-shelf software reaches its limits, I design algorithms tailored specifically to your unique problem. With my background as a PhD physicist, I understand complex data not just as a developer, but speak the language of science. If there is no existing solution, we build it together.

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Image Analysis & Computer Vision

Classic and AI-based pipelines (e.g., SAM 2, HRNet) for biological and medical image data. Cell segmentation, morphological quantification, object tracking, and automated feature extraction with sub-pixel precision.

OpenCVCellposeSAM 2HRNetNapari

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Scientific Software & GUIs

Custom desktop applications, interactive dashboards, and standalone deployment packages in Python, MATLAB, C++, C#, Java, and JavaScript. From research prototypes to commercial-grade tools with intuitive graphical interfaces.

MATLABPythonC++C#JavaJavaScriptPyQt

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Data Engineering & Pipelines

Scalable algorithms, mathematical modeling, and processing workflows for large-scale biophysical and experimental datasets. Reproducible and auditable from acquisition to publication.

JupyterNumPyPolarsSQL

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Scientific Consulting

Experimental design guidance, results interpretation, code architecture review, and technology migration. Bridging the gap between biological research questions and robust IT infrastructure.

ArchitectureCode MigrationExperimental Design

Software Tools

Products & Platforms

Software I develop is strictly confidential and 100% client-owned – no subscription models or recurring costs.

A notable exception is the FishInspector, which I have been developing as an open-source project alongside ongoing research for the Helmholtz Centre for Environmental Research since 2016. A significantly more powerful, commercial Pro version will be available shortly.

Open Source

An open-source software for the automated morphological feature assessment of zebrafish embryos. The accompanying publication has been cited over 100 times, highlighting the tool's widespread adoption in international research.

MATLAB Computer Vision GUI

View FishInspector

Commercial · Coming Soon

FishInspector Pro

The upcoming commercial release is designed as a high-performance local network server. Alongside significantly faster annotations, it features interactive data visualizations for intuitive, exploratory analysis directly in the browser. Teams can seamlessly evaluate results, generate comprehensive reports, and share them securely across the network.

Web UI Local Server Team Collaboration

Track Record

Selected Projects & Clients

Over a decade of delivering reliable scientific software to research institutions, biotech startups, and medical technology companies.

2016 - Present

Helmholtz Centre for Environmental Research - UFZ

Leipzig, Germany

Automated segmentation of zebrafish embryos in microscopic images for developmental toxicity screening
GUI development for visual inspection, manual correction, and quantitative data analysis
AI-powered image analysis pipeline using custom HRNet segmentation backend
3 peer-reviewed publications in Toxicological Sciences and Archives of Toxicology

MATLABPythonC#OpenCVHRNetPyTorch

2019 — 2024 · 4 yrs 7 months

Dewpoint Therapeutics GmbH

Dresden, Germany

Automated image analysis algorithms for high-throughput cell screening assays
Scientific consulting on experimental design and interpretation of results

MATLABPythonNapariCellposeC#Spotfire

2018 — 2020 · 2 yrs 3 months

Varian Medical Systems, Inc.

USA · Switzerland · Hungary

Maintenance and optimization of calibration software for clinical radiation devices
Porting MATLAB algorithms to C# and OpenCV in a microservices architecture
L3 customer support for deployed systems

MATLABC#OpenCV

2024 · 2 months

Open Sesame Therapeutics GmbH

Dresden, Germany

Jupyter notebooks for automated analysis of cell screening assay images
Custom Napari plugins for visualization and inspection of measurement data

PythonNapariCellposeJupyter

2014 — 2015 · 1 yr 6 months

RS-Zelltechnik GmbH

Leipzig, Germany

Real-time image processing for the detection of cellular deformations
Automated data pipeline for cell feature extraction
Internal web interface for data access and visualization

C++OpenCVPythonDjangoJavaScript

2013 — 2018 · 4 yrs 8 months

Mobius Medical Systems, LP

Houston, TX, USA

Maintenance and continuous development of complex end-user clinical software (DoseLab)
Level 3 customer support

MATLABPythonC++JavaHTMLJavaScript

2013 · 1 month

Link Analytics

Netherlands

Development of an algorithm for the visualization of economic networks
Implementation of a GUI for interactive data analysis

MATLAB

Social Proof

What Clients Say

Consistent 5-star feedback for professionalism, communication, and technical delivery.

★★★★★

Tobias did an excellent job on developing and maintaining DoseLab, and worked on transferring image processing functionality to C# and OpenCV in a microservices architecture. Even in the remote setup, communication on progress and achievements was transparent allowing for an efficient collaboration. Tobias is a dedicated and passionate software developer highly interested to gain domain knowledge. It was a great pleasure to work with Tobias and we highly recommend him.